A study on demographic and clinicopathological characteristics of severe acute pancreatitis in a tertiary-level intensive care unit in Nepal

BACKGROUND AND AIMS Severe acute pancreatitis can have serious consequences and a high mortality rate may necessarily require intensive care unit admission. This study is to describe the demographic clinicopathological characteristics of severe (SAP) in tertiary-level (ICU). METHODS The was designed retrospectively with diagnosis admitted adult ICU “between” January 2019 December 2022. RESULTS A total 52 patients were enrolled this study. maximum numbers between 41 years age, median age 47.6 years. Gallstone (biliary) identified as most important etiological factor associated pancreatitis. Among known factors, 52% cases related gallstone disease, 28.8% due alcohol, 7 (13.4%) other causes (such idiopathic, post-viral, post-ERCP, drug-induced), 5.7% triglycerides. In our study, common symptoms abdominal pain vomiting. And majority recovered conservative treatment. 48 (92.3%) improved, while 4 (7.6%) died. Eighteen (34.6%) required Mechanical ventilation (MV), 10 (19%) vasopressor supports. Eleven (21%) had evidence an kidney injury on Three (5.7%) underwent surgery, including necrosectomy open cholecystectomy. length stay 6.3 days. CONCLUSIONS cause gallstone, followed by alcohol-related. SAP seen more commonly male gender group 41-52 presenting Most could be managed conservatively.